Q9: Are STEVIA extracts safe for consumption by diabetics? Do they affect blood sugar levels?

Research has shown that STEVIA extracts DO NOT affect blood glucose levels or interfere with insulin.  With effectively zero calories, STEVIA extracts offer people with diabetes greater variety and flexibility in budgeting total calorie intake and assisting with weight management.  STEVIA extracts DO NOT have an effect on GI, at the levels of use. [34]


Q10: What is the Daily Acceptable Intake (ADI) of STEVIA?

Acceptable Daily Intake (ADI) is the amount of a food additive, expressed on a body-weight basis, which can be consumed in a diet every day throughout life without health risks.  It is the most important tool used by international scientific bodies to ensure the appropriate and safe use of food additives. Food and Agriculture Organization/World Health Organization’s Joint Expert Committee on Food Additives (JECFA) and the European Food Safety Authority (EFSA) use the same method to derive the Acceptable Daily Intake.

Based on a review of the current research available for STEVIA, the ADI was determined at four mg/kg body weight (measured as STEVIOL equivalents). [35] This number is set with a wide margin of safety and no adverse effects have been seen in intakes of STEVIA 100 times greater than the acceptable daily intake level.

To put this number into perspective, a 150-pound person would need to consume approximately 30 packets of a tabletop STEVIA sweetener.  Additionally, studies published in the May 2008 issue of Food and Chemical Toxicology showed that even very high amounts of STEVIA (comparable to a 150-pound person drinking 2,000 8-ounce servings of a 100% STEVIA-sweetened beverage) had no effect on general health.[36]

The above information and suggestions have been reviewed by Dr. Keith AYOOB, a member of the Global STEVIA Institute Advisory Board.


Q11: Are STEVIA extracts soluble? Are they stable under all PH conditions? Will STEVIA help prevent cancer?

STEVIA extracts have excellent solubility in a wide range of applications.  STEVIA extracts are extremely heat, photo and pH stable under a wide range of processing conditions and have exhibited excellent shelf stability.

pH meaning “potential hydrogen,” is a measure of hydrogen in concentration and is a measure of the acidity or alkalinity of a solution or substance.  When a solution or substance is alkaline or has alkalinity, it means it has the ability to neutralize acids.  Alkalinity is expressed as a pH number, on a scale of 0 to 14. A pH of 7 is neutral; neither acidic nor alkaline. A substance measuring a pH level between 7 and 14 is alkaline, and is called basic (or a base). The closer a substance is to pH 14, the more alkaline it is. [37]

Two of the main factors leading to cancer are an acidic pH and a lack of oxygen.  We know that cancer needs an acidic and low oxygen environment to survive and flourish.  If our pH level falls to 5.5 or below, our body simply cannot fight diseases as our pH is not properly balanced. [37]

STEVIA is, in fact, one of the high alkalizing sweeteners available that could help prevent cancer. [37] According to Dr. Ken Yasukawa in the 2002 issue of “Biological and Pharmaceutical Bulletin,” STEVIOL compounds and molecules derived from STEVIA leaves were tested for potential anti-cancer effects and the results were encouraging.  The STEVIOL molecules successfully blocked the effects of 12-Otetradecanoylphorbol-13-acetate or TPA in mice.  TPA is a potent carcinogen capable of spurring cancer growth.  By inhibiting the effect of TPA, extracted molecules from STEVIA might have an anti-cancer effect. [38]



Research and references:

(1) Origin of STEVIA (5th August, 2011 – STEVIANNA International Limited)

(2) Moises Santiago Bertoni (Wikipedia)

(3) FAQ – STEVIA (EUSA – European STEVIA Association)

(4) STEVIA (6th November, 2007 – Morita Kagaku Kogyuo Ltd.)

(5) The Healing Power of Natural Herbs (20th March, 2010 – Raintree Nutrition)

(6) STEVIA (September 2006 – University of Nebraska, Lincoln)

(7) Questions and Answers about STEVIA (STEVIA.com)

(8) The effect of STEVIOSIDE on blood pressure and plasma catecholamines in spontaneously hypertensive rats (Life Science 1998; 63(19)):1679-84 - Taipei Medical College Hospital and affiliated Taipei Wan Fang Hospital, Taiwan)

(9) Antihyperglycemic and blood pressure-reducing effects of STEVIOSIDE in the diabetic GOto-Kakizaki rat (Metabolism 2003 Mar;52(3):372-8 - – Arahus University Hospital, Denmark)

(10) Effects of STEVIA REBAUDIANA on glucose tolerance in normal adult humans (Braz J Med Biol Res. 1986;19(6):771-4 - Universidade de Maringá, Brasil)

(11) Increase of insulin sensitivity by STEVIOSIDE in fructose-rich chow-fed rats (Horm Metab Res. 2005 Oct;37(10):610-6 - National Pingtung University of Science and Technology, Taiwan)

(12) Antihyperglycemic effects of STEVIOSIDE in Type II diabetic subjects (Metabolism 2004 Jan;53(1):73-6 – Arahus University Hospital, Denmark)
[URL: http://www.ncbi.nlm.nih.gov/pubmed/14681845?dopt=Abstract]

(13) Evaluation of the carcinogenic potential of the intense natural sweeteners STEVIOSIDE and REBAUDIOSIDE A (Caries Res. 1992;26(5):363-6 – University of Illinois, Chicago 60612)

(14) Effect of STEVIOSIDE on growth and reproduction (Hum Reprod. 1991 Jan;6(1):158-65 - Chulalongkorn University Primate Research Centre, Faculty of Science, Bangkok, Thailand)

(15) STEVIA – Wikipedia

(16) Advantages of STEVIA (2008 – EverSTEVIA.com)

(17) Worldwide Studies and Research / Abstract on STEVIA (sweevia.com)

(18) STEVIOSIDE and related compounds: therapeutic benefits beyond sweetness (Pharmacol Ther 2009 Jan;121(1):41-54 – Mahidol University, Thailand)

(19)The Benefits of STEVIA Leaf Extracts (2010 – steviaplantextract.com)

(20)Benefits of STEVIA sweeteners (2012 – stevia-sweetener.com)

(21) Discover four fantastic benefits of STEVIA (15th January, 2011 – NaturalNews.com)

(22) Stay Healthy the STEVIA Way (Diabetics, Weight Loss, Children – Ray Sahelian, MD / Healthy.net)

(23) Risk in Belief: STEVIOL GLYCOSIDES in Food (August 2010 – Centre for Food Safety)

(24) Permitted Sweeteners in Food Regulation (Chapter 132U – attachment)

(25) STEVIA Regulatory Environment (2012 – GLG Life Tech Corporation)

(26) Summary and Conclusions of the sixty-ninth meeting of the Joint FAO / WHO Expert Committee on Food Addictives (17 – 26th June, 2008 – WHO)

(27) FDA Clears Use of Herbs as Sweetener (18th December, 2008 – Wall Street Journal)

(28) Notice to the U.S. FDA that the use of REBAUDIOSIDE A derived from STEVIA as a food ingredient is Generally Recognized as Safe (Jan. 2009 – attachment)

(29) The CE regulation establishes STEVIOL GLYCOSIDES as food additive (15th November, 2011 – Commission Regulation (EU) No. 1131 / 2011 p. 26 & p. 39)

(30)France approves high Reb A STEVIA sweetener (8th September, 2008 – foodnavigator.com)

(31) STEVIA Sales to Reach $825 Million by 2014 (11th February, 2011 – NASDAQ.com)

(32) STEVIA Market Share to Explode in 2011, says Report (1st September, 2011 – foodnavigator-usa.com)

(33) STEVIA is Replacing Sugar and Sweeteners in Food and Beverages (26th August, 2011 - investinSTEVIA.com)

(34) FAQ – International STEVIA Council (2012 – International STEVIA Council)

(35) Scientific Opinion on the safety of STEVIOSIDE glycosides for the proposed uses as a food additive: EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS). EFSA Journal.2010; 8(4):1537.

(36) Carakostas M, et al. Overview: the history, technical function and safety of REBAUDIOSIDE A, a naturally occurring STEVIOL glycoside, for use in food and beverages. Food and Chemical Toxicology. 2008; 46:S1-S10.

(37) pH Levels and Cancer, Alkaline and Acidic Foods (26th February, 2012 – Health, Food News & Big Pharma)

(38) STEVIA and Cancer (11th January, 2011 – LIVESTRONG.com)
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